WebDec 14, 2005 · Brn3a is coexpressed extensively with the closely related factor Brn3b in the embryonic retina, and the effects of the loss of Brn3a in retinal development are not severe, suggesting partial redundancy of … POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor … See more Brn3a was initially discovered in mice based on homology to the prototypal POU transcription factors Pit1 (Pituitary-specific positive transcription factor 1, Pou1f1), Oct1 (Pou2f1), and the Caenorhabditis elegans factor … See more In addition to sensory neurons, in rodents and birds (and presumably humans) Brn3a is expressed in multiple sites in the central nervous system, including the spinal cord, midbrain superior … See more • Eng SR, Lanier J, Fedtsova N, Turner EE (Aug 2004). "Coordinated regulation of gene expression by Brn3a in developing sensory ganglia". … See more POU4F1 has been shown to interact with Estrogen receptor alpha, RIT2 and Ewing sarcoma breakpoint region 1. See more • BRN-3 See more • POU4F1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine See more
Molecular analysis of oncogenicity of the transcription factor, BRN3A …
WebSep 1, 2024 · Abstract. Background: Brn3a/Pou4f1 is a class IV POU domain-containing transcription factor and has been found to be expressed in a variety of cancers. … WebResearch Information. Brn-3a Antibody (14A6) is an IgG 2b κ mouse monoclonal Brn-3a antibody (also designated BRN3A antibody, POU4F1 antibody, or POU class 4 … payment on disney vacation
Molecular codes for cell type specification in Brn3 retinal ... - PNAS
WebEntrez Gene Summary. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in … WebJan 1, 2024 · Using Brn3a and Brn3b mutant mice in which the alkaline phosphatase gene was knocked-in (Badea et al. [Neuron] 2009;61:852-864; Badea and Nathans [Vision Res] 2011;51:269-279), we studied the general effects after gene removal on the retinal neuropil together with the consequences of lack of development of large numbers of GCs onto the ... WebRabbit polyclonal purified antibody. Cat. No. 411 003. 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for … payment on filing meaning