Circwhsc1

WebDec 29, 2024 · CircWhsc1, a hypoxia-inducible circRNA, is highly expressed in cardiac ECs. (A) Screened circRNAs that are highly expressed in neonatal rodent hearts, … WebMay 7, 2024 · CircWHSC1 expression in normal endometrial and endometrial cancer tissues was detected using PCR. Overexpression or knockdown of circWHSC1 in endometrial cancer cell lines HEC‐1B or Ishikawa, respectively, cell function experiments were used to detect the impact of circWHSC1 on endometrial cancer cells. A nude …

Aging-specific changes in cardiomyocyte transcriptome at single …

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Extracellular vesicle-derived CircWhsc1 Promotes Cardiomyocyte ...

WebMar 9, 2024 · CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer. Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic beta-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression. WebJan 6, 2024 · CircWHSC1 functioned as the sponge for miR‐142‐3p, which directly targeted HOXA1. Inhibition of miR‐142‐3p ameliorated the effects of circWHSC1 knockdown on HCC cell proliferation and metastasis. Moreover, miR‐142‐3p overexpression restrained the growth and motility of HCC cells, with HOXA1 elevation reversing the impacts. ... WebIntroduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous … on one\u0027s way to什么意思

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Category:Extracellular vesicle-derived CircWhsc1 promotes …

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Circwhsc1

401 Wych Cir, Crestview, FL 32536 Trulia

WebDec 31, 2024 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate … WebCircWHSC1 functioned as the sponge for miR-142-3p, which directly targeted HOXA1. Inhibition of miR-142-3p ameliorated the effects of circWHSC1 knockdown on HCC cell …

Circwhsc1

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Webboth circWHSC1 overexpressed and down-regulated cell lines were further selected with 2 μg/mL puromycin. The sequences of circWHSC1 and shRNA can be found in Additional file 1:TableS3. MTT assay The circWHSC1 overexpressed and down-regulated cells with control group were counted and seeded in 96-well plates. 0h, 24h, 48h and 72h after … WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues.

WebMar 2, 2024 · The interplay among circWHSC1, miR-532-3p, and latent transforming growth factor-β binding protein 2 (LTBP2) was confirmed by luciferase reporter and biotinylated … WebApr 29, 2024 · The enclosed configuration of circRNAs protects them from degradation and potentiates them as biomarkers. Several circRNAs such as circMUC16, circRNA_MYLK, circRNA-UBAP2, circWHSC1, hsa_circ_0013958, circFGFR3, hsa_circRNA_102958 and circ_0072995 have been found to be up-regulated in this cancer, acting as oncogenes.

WebDec 1, 2024 · CircWHSC1 [170] and circPUM1 [77] were reported to not only promote EOC cell proliferation, migration and invasion by sponging miRNAs but also act on the peritoneum in an exosome-dependent manner ... WebMay 7, 2024 · CircWHSC1 expression in normal endometrial and endometrial cancer tissues was detected using PCR. Overexpression or knockdown of circWHSC1 in …

WebCompared with vector transfected group, subcutaneous injection of circWHSC1-overexpressed cells showed a more rapid rate of growth and larger tumor volume (a, b). The expression of circWHSC1 was ...

WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues. inwin x-frame 2.0WebDec 1, 2024 · CircWHSC1 overexpressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR‐646, which was confirmed using … inwin x frameWebCircWHSC1 overexpression promoted the proliferation, migration and invasion of endometrial cancer cells and decreased apoptosis. CircWHSC1 knockdown had the opposite effect. CircWHSC1 overex-pressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR-646, which was confirmed using … inwin x-frameWebIntroduction. Non-small cell lung cancer (NSCLC) takes up 80% of all lung cancer cases and is the most common type of human lung cancer. 1 Although surgery, radiotherapy, and chemotherapy have great progress, the 5-year survival rate of NSCLC patients is still less than 19% due to relapse and drug resistance, and the lack of sensitive and efficient early … inwin x-frame 2.0 test bench caseWebNov 3, 2006 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate and G2/M … in win 迎廣 chopin pro bWebDec 1, 2024 · CircWHSC1 overexpressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR‐646, which was confirmed using luciferase reporter gene assays. in winzip a virusWeb(D, E) MCF7 cells were transfected with miR-195-5p mimics and circWHSC1 overexpressing plasmids, and qRT-PCR was carried out to determine the expression of miR-195-5p (D) and circWHSC1 (E). inwi offre *6