Cisplatin pubmed
WebCisplatin induces apoptosis of A549 cells by downregulating peroxidase V Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. WebOct 5, 2014 · Cisplatin derivatives are used as the mainline treatment of ovarian cancer, …
Cisplatin pubmed
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WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class … WebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular …
WebCisplatin / metabolism Cisplatin / pharmacology* Cisplatin / therapeutic use Combined … WebCisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc.
WebCisplatin is a widely used anti-cancer drug that is exceptionally effective against … WebMar 2, 2024 · Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer …
WebOct 7, 2024 · Cisplatin is one of the most widely used chemotherapeutic drugs in the …
WebAims: This study investigated the regulatory effect of Mitofusin2 (Mfn2) on mitochondria-associated endoplasmic reticulum membrane (MAMs) integrity and cellular injury in cisplatin-induced acute kidney injury (CP-AKI). Results: CP- AKI mice exhibited decreased expression of Mfn2, increased expression of phosphorylated adenosine monophosphate … theraband wandstationWebAll studies in which mannitol was used for forced diuresis with cisplatin therapy were evaluated. Data synthesis: Cisplatin therapy can lead to transient and permanent renal impairment. Molecular and histologic changes occur … sign in upstox accountWebWe demonstrate that cisplatin-induced transition from epithelial to mesenchymal … sign in ups storeWebDec 1, 2024 · Methods. In this open-label, randomized, phase III study, newly diagnosed patients with advanced NSCLC were initially randomized (R1, 1:1) to receive first-line treatment with cisplatin 75 mg/m 2 plus docetaxel 75 mg/m 2 (DC75) or 60 mg/m 2 (DC60) for up to 4 cycles. Patients without progression were further randomized (R2, 1:2) to best … thera band wall systemWebCisplatin-resistant bladder cancer overexpresses particular sugar chains compared with chemotherapy-naïve bladder cancer. Using a recombinant protein from the malaria parasite Plasmodium falciparum, we can target these sugar chains, and our results showed a significant antitumor effect in cisplatin- … theraband wall unitWebJan 28, 2024 · In this study, we sought to provide a comprehensive review of the current state of the science highlighting the use of cisplatin in cancer therapy, with a special emphasis on its molecular mechanisms of action, and treatment modalities including the combination therapy with natural products. theraband wall station accessoriesWebJul 1, 2024 · Using the platinum-based chemotherapy cisplatin as a model for CICI, we show here that cisplatin suppresses nicotinamide adenine dinucleotide (NAD +) levels in the adult female mouse brain in vivo and in human cortical neurons derived from induced pluripotent stem cells in vitro. theraband wall walks